Hypertriglyceridemia as an independent predictor of adverse prognosis in female patients with acute myocardial infarction: a comprehensive retrospective cohort study.

ABSTRACT:

Background

Acute myocardial infarction (AMI) has notable sex-specific differences in clinical outcomes. While low-density lipoprotein cholesterol (LDL-C) is a longstanding core for atherosclerotic cardiovascular disease (ASCVD) risk assessment, the prognostic value of hypertriglyceridemia (HTG) in AMI patients-especially its sex-specific impact-remains unclear. This gap is critical as HTG is more common in women but understudied in post-AMI populations.

Methods

A retrospective cohort included 850 consecutive AMI patients (412 females, 438 males) admitted to the Seventh Affiliated Hospital of Sun Yat-sen University (Jan 2019-Dec 2024), stratified by HTG (triglycerides ≥2.2 mmol/L). Median follow-up was 2.6 years, with outcomes: all-cause death, heart failure, major adverse ca

SUBMITTER: Ma S 

PROVIDER: S-EPMC12739952 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature