The effects of transcutaneous auricular vagus nerve stimulation in epilepsy comorbid with migraine on the EEG power spectrum: a randomized controlled trial.

ABSTRACT:

Background

Migraine is a common comorbidity in patients with epilepsy, with a comorbidity rate ranging from 9.3 to 34.7%. Transcutaneous auricular vagus nerve stimulation (taVNS) is an emerging therapy used in both epilepsy and migraine treatment. However, there are currently no randomized controlled studies (RCTs) using taVNS for epilepsy complicated with migraine.

Objective

In this study, we evaluated the effect of taVNS as an adjuvant therapy on patients with comorbid epilepsy and migraine.

Methods

Forty comorbid patients (taVNS n = 20, tanVNS n = 20) were recruited and randomly grouped. The taVNS group received the true stimulus, whereas the tanVNS group received a pseudostimulus. Outcome assessment was performed at baseline and 24 weeks after initia

SUBMITTER: Ma S 

PROVIDER: S-EPMC12740757 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature