Home-Combo: an online home-based exercise intervention for women with breast cancer undergoing neoadjuvant chemotherapy: study protocol for a 2-arm pragmatic randomized controlled trial.

ABSTRACT:

Background

Chemotherapy carry side effects and potentially result in dose decreases or treatment delays of women with breast cancer (BC). Relative dose intensities of chemotherapy <85% are associated with a worse disease prognosis and lower treatment efficacy. Exercise may modulate treatment response through its effects on tumor microenvironment. Home-based exercise is a convenient strategy, proven to be effective and beneficial for women with a BC diagnosis under treatment. Recent evidence suggests that exercise may contribute to tumor regression neoadjuvant treatment. Studies investigating the effects of exercise interventions on chemotherapy completion rates are needed. No study appears to have analyzed the effects of a home-based exercise interventions on tumor regression in wo

SUBMITTER: Ramos PGF 

PROVIDER: S-EPMC12740911 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature