Temporal trends in mortality involving atrial fibrillation and rheumatic heart disease: a 25-year nationwide analysis.

ABSTRACT:

Background

Atrial fibrillation (AF) and rheumatic heart disease (RHD) can coexist with potential for serious complications. Trends involving both conditions remain unexplored and this study aims to explore them.

Methods

Nationwide mortality records were obtained from the Centers for Disease Control and Prevention Wide-Ranging Online Data for Epidemiologic Research (CDC-WONDER) database from 1999 to 2023 among U.S. adults >45 years with AF (ICD-10 code: I48) and RHD (I05-I09). Age-adjusted mortality rates (AAMRs) were calculated per 100,000 population and stratified by demographic variables. Joinpoint regression analysis was used to determine the average and annual percent change (AAPC and APC).

Results

From 1999 to 2023, a total of 36,701 deaths were reported among in

SUBMITTER: Hemida MF 

PROVIDER: S-EPMC12741100 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature