Exploring Social and Structural Determinants of Substance Use Among Sexual and Gender Minority Adults in the United States.

ABSTRACT: PurposeTo identify key social and structural factors associated with hazardous alcohol and problematic drug use among sexual and gender minority (SGM) adults.MethodsWe conducted a cross-sectional secondary analysis of 2016 to 2019 data from the Generations Study, a probability sample of 1518 SGM adults. Hazardous alcohol and problematic drug use were measured using the Alcohol Use Disorder Identification Test-Consumption (AUDIT-C) and Drug Use Disorder Identification Test (DUDIT). Candidate predictors included sociodemographic characteristics, minority stressors, adverse childhood experiences, health indicators, and social support. Interpretable machine-learning models with SHapley Additive exPlanations characterized multilevel correlates of 3-level risk categories.ResultsHazardous alcohol

SUBMITTER: Zhang C 

PROVIDER: S-EPMC12741260 | biostudies-literature | 2025 Jan-Dec

REPOSITORIES: biostudies-literature