Sex differences in the association of social determinants of health and adverse cardiovascular outcomes in patients with atrial fibrillation.

ABSTRACT:

Background

Despite anticoagulation, patients with atrial fibrillation (AF) experience persistent elevated cardiovascular risk, with conflicting evidence regarding sex-based outcome disparities. Social determinants of health (SDOH)-encompassing economic, psychosocial and environmental factors-demonstrate robust associations with cardiovascular outcomes and exhibit significant sex-specific patterns, yet remain understudied in AF populations. This study aimed to clarify sex differences in the association of SDOH and adverse cardiovascular outcomes in patients with AF.

Methods

Data came from the UK Biobank. Participants with AF enrolled between 2006 and 2010 were included. SDOH comprised economic, psychosocial and neighbourhood environmental factors. The primary outcome was a co

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC12742081 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature