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Impact of depression on medication non-adherence in coronary artery disease: a systematic review and meta-analysis.


ABSTRACT:

Background

Depression is a risk factor and complication of coronary artery disease (CAD) that is associated with poor cardiovascular outcomes. This may be related to medication non-adherence; a topic on which considerable new evidence has emerged. We aim to assess the relationship between depression and medication adherence in patients with CAD.

Methods

The Cochrane Library, Medline and Embase databases were searched for relevant studies published until January 2023. Studies were included if they reported the prevalence of adherence to cardiovascular medications in depressed versus non-depressed participants aged >18 years with CAD, including acute and chronic coronary syndromes and those undergoing percutaneous coronary intervention. The primary outcome was the OR of non-ad

SUBMITTER: Jones DL 

PROVIDER: S-EPMC12742177 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature