Implementation of Single-Pill Combination Medication for Hypertension Treatment by Nonphysician Health Care Workers at Primary Healthcare Facilities in Nigeria: An Explanatory Mixed Methods Study.

ABSTRACT:

Background

Single-pill combination (SPC) therapy improves hypertension control; however, its implementation in primary care settings remains limited. In Nigeria, there is insufficient evidence on factors influencing SPC uptake, particularly from the perspective of healthcare workers (HCWs). This study examined the implementation of SPC medications for hypertension treatment by nonphysician HCWs at primary healthcare facilities (PHCs) in Nigeria.

Methods

An explanatory sequential mixed methods study was conducted, building on a cluster randomized controlled trial embedded within the Hypertension Treatment in Nigeria Program. The trial compared SPC medications with free-equivalent combination therapies across 60 PHCs (January-June 2021). A subsequent qualitative component (Sep

SUBMITTER: Okpetu EI 

PROVIDER: S-EPMC12742375 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature