Persistence of human enteric viruses in artificial and human saliva.

ABSTRACT: Enteric viruses, such as Adenovirus 41 (AdV41) and Coxsackievirus B3 (CVB3), are significant contributors to gastrointestinal infections, particularly among young children and immunocompromised individuals. While fecal-oral transmission is the primary route of infection, emerging evidence indicates that saliva may also function as a reservoir for these viruses, posing a potential risk for oral transmission. Previous studies have primarily focused on the decay of viruses in aqueous matrices, like wastewater and freshwater, but the persistence of these viruses in human saliva remains underexplored. This study aimed to investigate the persistence of AdV41 and CVB3 in both human and artificial saliva under various conditions, including the presence of fecal particles and specific oral bacteria

SUBMITTER: Kosgei SC 

PROVIDER: S-EPMC12742735 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature