Intrinsic and extrinsic risk factors in tumor-related epilepsy.

ABSTRACT:

Purpose

This study consolidated evidence on the association of tumor-intrinsic and investigated the underexplored association of tumor-extrinsic factors with tumor-related epilepsy, aiming to contribute to the overall risk assessment for clinical management in tumor-related epilepsy.

Material & methods

Over a period of one year (2020), we prospectively collected imaging and clinical data of 373 patients with histopathologically confirmed brain tumors. Assessed tumor-intrinsic factors included histopathology, diameter and anatomical location, with the central lobe comprising the precentral, postcentral and subcentral gyrus and paracentral lobule. Tumor-extrinsic factors comprised sex, age, BMI, smoking, alcohol abuse, and Na⁺/K⁺ imbalances. We applied un

SUBMITTER: Rafi O 

PROVIDER: S-EPMC12743018 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature