Tumor Control After Radiosurgery in Sporadic and Neurofibromatosis Type 2 Vestibular Schwannomas.

ABSTRACT:

Introduction

The tumor control rate after stereotactic radiosurgery (SRS) for neurofibromatosis type 2-associated vestibular schwannomas (NF2-VSs) compared to sporadic vestibular schwannomas (S-VSs) remains unclear. This nationwide, multicenter, retrospective study (KGKRS-21-001) aimed to clarify this issue.

Methods

A total of 4718 patients treated with SRS for vestibular schwannomas were analyzed from 13 nationwide institutions in Korea. NF2-VS cases were propensity score-matched with S-VS cases at a ratio of 1:1, based on age, tumor volume, and marginal dose, resulting in 122 cases in each group.

Results

No significant differences in age, tumor volume, or marginal dose were observed between the matched cohorts. The overall tumor control rates at 1, 3, and 10 years a

SUBMITTER: Ji SY 

PROVIDER: S-EPMC12743036 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature