Diagnostic accuracy of dual-layer spectral CT for osteolytic vertebral metastases.

ABSTRACT:

Objectives

To evaluate whether dual-layer spectral computed tomography, compared with conventional CT, improves diagnostic accuracy for osteolytic vertebral metastases. Furthermore, to investigate the influence of dual-layer CT on the subjective visibility of metastases.

Materials and methods

In this single-center retrospective study, consecutive patients with an untreated primary tumor who underwent dual-layer CT and either MRI or PET-CT as reference standard within 14 days were included. Two independent observers, blinded to the reference, performed two scorings. First, the conventional CT was scored and the results were recorded. Subsequently, Calcium suppression, monoenergetic (monoE40 and monoE200), and Z-effective reconstructions were added. Subjective visibility was c

SUBMITTER: van der Star S 

PROVIDER: S-EPMC12743067 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature