Feasibility and Safety of a Single-Session of Transcutaneous Cervical Magnetic Stimulation, taVNS, and iTBS on Heart Rate Variability, Safety, and Pain Modulation.

ABSTRACT: The autonomic nervous system (ANS) plays a crucial role in maintaining homeostasis, and its dysfunction is linked to numerous clinical conditions, including chronic pain. Neuromodulatory interventions such as transcutaneous auricular vagus nerve stimulation (taVNS), transcutaneous cervical magnetic stimulation (tCMS), and intermittent theta burst stimulation (iTBS) have been investigated for their potential to modulate autonomic responses and pain perception. However, the efficacy and safety of these techniques remain unclear. This study aimed to evaluate the feasibility and safety of a single session of neuromodulatory stimulation in modulating autonomic function and pain processing in healthy individuals. A double-blind, randomized, crossover clinical trial was conducted with 22 healthy

SUBMITTER: Lopes TDS 

PROVIDER: S-EPMC12743293 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature