Green-synthesized silver nanoparticles from Camellia sinensis: mechanistic insights into phenolic-mediated multifunctional biological activities.

ABSTRACT:

Background

Green synthesis of silver nanoparticles (AgNPs) using plant extracts provides an eco-friendly route that bridges phytochemistry with nanobiotechnology. Camellia sinensis, rich in polyphenols, serves as an effective reducing and stabilizing agent in this process.Ethanolic extracts of C. sinensis leaves were characterized for phenolic composition by HPLC-DAD and utilized for AgNP synthesis (CS-AgNPs). The nanoparticles were characterized by UV-Vis, FTIR, XRD, SEM, EDX, and DLS. Biological properties were assessed through antioxidant (DPPH, ABTS), antibacterial (Gram-positive and Gram-negative strains), anti-inflammatory (BSA denaturation), and enzyme inhibitory (urease, α-glucosidase) assays, supported by molecular docking.

Results

EGCG was the dominant phenolic com

SUBMITTER: Demir A 

PROVIDER: S-EPMC12743403 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature