Age-related changes in the transcriptomic profile associated with ovarian small white follicle recruitment in commercial laying hens.

ABSTRACT: Egg production efficiency in poultry relies on the number of ovarian follicles selected for ovulation or atresia. Hens experience a gradual decline in reproductive efficiency as they age. However, the molecular mechanisms responsible for the decrease in small white follicles with age remain poorly understood. This study aimed to identify genes and biological pathways regulating the recruitment of small white follicles across different production cycles. Hy-line W-36 laying hens were obtained from a commercial poultry farm in three different age groups (n=15/group): 37 weeks (peak laying phase) as a control, 67 weeks (intermediate laying phase), and 87 weeks (late laying phase). Small white follicles from the ovaries (n =15/group) were collected for transcriptomic analysis. Total RNA was is

SUBMITTER: Poudel S 

PROVIDER: S-EPMC12743439 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature