Hydrogen excess drives metabolic reprogramming and viral dynamics in syngas-converting microbiomes.

ABSTRACT: Microbial communities drive essential bioprocesses, including the conversion of synthesis gas into biomethane, a sustainable energy source that supports circular carbon economies. In anaerobic environments, specialized consortia of bacteria and archaea facilitate syngas methanation through syntrophic interactions, where hydrogenotrophic methanogens play a central role in reducing carbon dioxide and monoxide with hydrogen. However, imbalances in gas ratios, particularly excess hydrogen, can disrupt these interactions and impair overall efficiency. Yet, the molecular mechanisms underlying microbial responses to such imbalances remain poorly understood. Here we show that hydrogen excess triggers profound metabolic and viral remodeling in a thermophilic anaerobic microbiome, leading to reduced

SUBMITTER: Ghiotto G 

PROVIDER: S-EPMC12743542 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature