Tumor enhancement by magnetic resonance imaging after endoscopic ultrasound-guided radiofrequency ablation for small pancreatic neuroendocrine tumors.

ABSTRACT:

Background and aims

Pancreatic neuroendocrine tumors (PNETs) are rare and often diagnosed at advanced stages, limiting curative options. For PNETs <20 mm, endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) has emerged as a minimally invasive therapeutic alternative. This study investigates the role of magnetic resonance imaging (MRI) in monitoring postablation enhancement, emphasizing its utility in assessing treatment efficacy.

Methods

Four PNETs in the uncinate process, measuring <15 mm, underwent EUS-RFA (insulinomas [2 patients]; nonfunctioning PNETs [2 patients]). MRI was performed immediately (2 patients) and 30 days (2 patients) after EUS-RFA to confirm tumor destruction, with enhancement analysis as the main marker of effective ablation.

Results

Th

SUBMITTER: Ardengh AO 

PROVIDER: S-EPMC12744747 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature