Relationships Between Metabolic and Bariatric Surgery and Adverse Kidney Outcomes: An Analysis of a Retrospective Cohort.

ABSTRACT:

Objective

Obesity is associated with an increased risk of chronic kidney disease. Metabolic and bariatric surgery (MBS) is currently the most effective intervention for sustained weight loss and may reduce the risk of obesity-associated kidney disease. This study examined the relationships between MBS and adverse kidney outcomes.

Methods

This retrospective cohort analysis included 4322 patients with obesity, with or without type 2 diabetes mellitus (T2D), who underwent MBS, and 30,919 nonsurgical control patients from a large health system within the state of Indiana. A primary kidney composite [≥ 1 estimated glomerular filtration rate (eGFR) < 15 mL/min/1.73 m², ≥ 1 eGFR measurement with a ≥ 40% decrease from baseline, or kidney failure-related death], as well as

SUBMITTER: Maki KC 

PROVIDER: S-EPMC12744858 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature