Longitudinal trajectories of left ventricular myocardial remodeling: associations with cardiovascular risk factors in the multi-ethnic study of atherosclerosis.

ABSTRACT:

Background

Understanding the influence of cardiovascular risk factors on longitudinal cardiac remodeling requires three-dimensional analysis of longitudinal shape changes beyond scalar indicators such as mass and volumes. The aim of this study is to determine trajectories of cardiovascular risk factor-related remodeling in a large cohort imaging study.

Methods

We examined 2521 participants (54% female, aged 60±9 years) of the multi-ethnic study of atherosclerosis (MESA) at baseline and after 10years. Myocardial remodeling was assessed by longitudinal left ventricular shape trajectories derived from cardiac magnetic resonance imaging using a statistical shape atlas. Penalized logistic regression was used to examine the associations between trajectory scores and cardiovascular

SUBMITTER: Mauger CA 

PROVIDER: S-EPMC12745149 | biostudies-literature | 2025 Winter

REPOSITORIES: biostudies-literature