Case Report: Biweekly TAS-102 and bevacizumab as maintenance therapy for recurrent and metastatic pseudomyxoma peritonei following palliative cytoreduction.

ABSTRACT:

Introduction

Recurrence of pseudomyxoma peritonei (PMP) with pulmonary and lymphatic metastases occurs only rarely in clinical practice, making the selection of an appropriate postoperative chemotherapy regimen essential for managing these complex cases.

Case presentation

We describe an 83-year-old woman with an appendiceal pseudomucinous tumor who developed a recurrence 2 years after initial surgery, presenting with bilateral lung metastases and multiple lymph node metastases. Palliative cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) was performed to relieve intestinal obstruction. Given the patient's advanced age and the complexity of the procedure, the completeness of the cytoreduction score was 2, and the peritoneal cancer ind

SUBMITTER: Wang B 

PROVIDER: S-EPMC12745458 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature