Molecular detection of antimicrobial resistance in livestock mycoplasmas: current status and future prospects.

ABSTRACT: Pathogenic Mycoplasma species significantly impact livestock health, causing respiratory, articular, mammary gland, and reproductive disorders with substantial economic losses. Antimicrobials remain essential for controlling clinical signs and production losses; however, treatment efficacy is increasingly threatened by antimicrobial resistance (AMR). Phenotypic methods remain the most reliable approach for detecting AMR in Mycoplasma species; however, they are time-consuming, technically demanding, and results are often difficult to interpret. The absence of clinical breakpoints and limited epidemiological cut-off values (ECOFFs) further complicate AMR categorization. Advances in molecular techniques offer a promising alternative for faster AMR detection and prediction. This

SUBMITTER: Sulyok KM 

PROVIDER: S-EPMC12745486 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature