Quality of Life and Return to Work After Radiotherapy in Young Adults With Head-and-Neck Cancer-A Bicentric Cross-Sectional Observational Study.

ABSTRACT:

Objective

Young adults (18-45 years) with head-and-neck cancer represent a unique population with limited data on quality of life (QoL) and return-to-work after radiotherapy. This bicentric study aimed to evaluate these outcomes.

Methods

Conducted at two comprehensive cancer centers, the study included young head-and-neck cancer survivors treated with curative radiotherapy between 2003 and 2023. QoL was assessed with EORTC QLQ-C30 and HN43; distress, depression, and anxiety with the NCCN Distress Thermometer, PHQ-9, and GAD-7; fear of cancer progression and work ability with FoP-Q-SF and WAI.

Results

Out of 83 eligible patients, 58 (70%) participated. The median age at radiotherapy was 41 years, with a balanced gender distribution (40% female, 60% male). The median ti

SUBMITTER: Pannenbecker C 

PROVIDER: S-EPMC12745888 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature