<i>Saccharomyces cerevisiae</i>-Fermented Salmon Placental Protein Inhibits Muscle Loss in a Mouse Model of Sarcopenia.

ABSTRACT: Addressing sarcopenia and frailty in aging populations is crucial for improving quality of life and reducing healthcare dependence among these patients. Although no specific drugs have been approved for treating sarcopenia, protein supplements rich in branched-chain amino acid (BCAA) have been reported to increase muscle mass and function in elderly individuals. Fermentation of salmon placenta protein is an effective approach to improve BCAA content compared to previous sarcopenia-related protein supplements. Therefore, this study aimed to evaluate BCAA content through salmon placenta protein (Sal) fermented with Saccharomyces cerevisiae (F-Sal), analyze the expression of muscle-forming genes in C2C12 myoblasts in vitro, measure the weight gain of quadriceps femoris and gastrocnemiu

SUBMITTER: Lee JC 

PROVIDER: S-EPMC12745894 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature