Ultrasound-Assisted Extraction Using a 3D-Printed Device Functionalized With SPE Sorbent for UHPLC-DAD Analysis of Pesticide Residues in Honey.

ABSTRACT: The presence of pesticide residues in honey represents a significant concern for food safety and public health, underscoring the need for advanced analytical techniques capable of ensuring accurate detection and effective food control. In this study, a stereolithographically 3D-printed device coated with the solid-phase extraction (SPE) sorbent Oasis MCX was developed for the ultrasound-assisted extraction (UAE) of pesticide residues in honey, followed by ultra-high performance liquid chromatography with diode array detection (UHPLC-DAD) analysis. Variables that affect the performance of the 3D-printed extraction (i.e., design and fabrication of 3D-printed device, SPE resin, elution solution, pH, and ultrasonic conditions) and the chromatographic analysis were systematically evaluated. The

SUBMITTER: Lupu D 

PROVIDER: S-EPMC12745918 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature