Smartphone-Based Colorimetric Determination of Imeglimin Hydrochloride Using Eosin Y: A Simple and Eco-Friendly Analytical Approach.

ABSTRACT: A simple, rapid and eco-friendly smartphone-assisted colorimetric method was developed for the determination of imeglimin hydrochloride (IMG) in pharmaceutical dosage forms. The method is based on the formation of an orange-coloured ion-pair complex between eosin Y (EY) and the amine group of IMG through electrostatic interactions in an acidic medium. The intensity of the resulting colour was quantified using a smartphone camera, and the colour parameters were analysed using ImageJ software and the colour detector application. The absorbance of the resulting IMG-EY complex was recorded spectrophotometrically at the maximum wavelength of 524 nm. The smartphone and spectrophotometric approaches exhibited a linear response in the concentration range of 0.8-10 µg/mL, showing satisfactory accur

SUBMITTER: Barseem A 

PROVIDER: S-EPMC12746043 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature