Cross-Sectional and Longitudinal Associations of Irisin and Adiponectin With Obesity, Sarcopenia and Sarcopenic Obesity.

ABSTRACT:

Background

Irisin, an exercise-induced myokine and adiponectin, an adipocyte-derived hormone, are involved in energy metabolism and musculoskeletal health. However, their associations with obesity, abdominal obesity, sarcopenia and sarcopenic obesity remain unclear, and longitudinal evidence is limited. This study investigated the cross-sectional and longitudinal associations of these biomarkers with obesity- and sarcopenia-related outcomes.

Methods

We used data from the Hallym Aging Study, a cohort of Korean adults aged ≥ 45 years (45-64 years: 30%, ≥65 years: 70%). The cross-sectional analysis used the third wave (2010), while the longitudinal analysis included the second (2007, baseline) and third waves. In both analyses, sex-specific tertile groups (T1, T2 and T3) were d

SUBMITTER: Kim Y 

PROVIDER: S-EPMC12746044 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature