Noninvasive electrodiagnostic and motor function assessment of the common fibular nerve regeneration in the rabbit hindlimb.

ABSTRACT:

Background

Although widely used, the rat model remains poorly transferable to humans for peripheral nerve regeneration studies. The rabbit is a much better choice from an anatomical perspective. However, it remains little used due to the lack of available literature. The aim of this article is to demonstrate the feasibility and effectiveness of an electrophysiological protocol combined with a motor function assessment to analyze nerve repair.

Methods

Ten white New Zealand rabbits underwent a 4 cm transection of the fibular nerve. Autograft regeneration over 36 weeks was compared to non-repaired controls. The compound muscle action potential (CMAP) was recorded in the tibialis anterior and the extensor digitorum brevis. An electromyogram (EMG) was obtained after needle insert

SUBMITTER: Larrivee O 

PROVIDER: S-EPMC12746178 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature