Ophthalmic artery Doppler and carotid intima-media thickness 3-6 years postpartum in women with and without a history of placental insufficiency.

ABSTRACT:

Introduction

Preeclampsia and fetal growth restriction, which are clinical presentations of placental dysfunction, are frequently associated with angiogenic imbalance during pregnancy and increased long-term cardiovascular risk. Whether this risk is driven by the pre-pregnancy risk factors, clinical disease, or by an elevated sFlt-1/PlGF ratio remains unclear. This study aimed to assess the association between vascular assessments (ophthalmic artery Doppler and carotid intima-media thickness) 3-6 years postpartum and a history of preeclampsia and fetal growth restriction, and to evaluate if associations were impacted by an angiogenic imbalance during pregnancy.

Material and methods

This was a cross-sectional study, which included individuals prospectively recruited during th

SUBMITTER: Garcia-Manau P 

PROVIDER: S-EPMC12746186 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature