Pregnancy and perinatal outcomes after day 5 versus day 6 blastocyst-stage embryo transfer: A systematic review and meta-analysis.

ABSTRACT:

Introduction

Embryo transfer at the blastocyst stage has become popular in assisted reproductive technology, but it is still a challenge for embryologists to select the embryos with the highest implantation potential. We aimed to investigate whether blastocyst development speed and blastocyst quality affect pregnancy and perinatal outcomes in single frozen-thawed blastocyst transfer (SFBT) cycles.

Material and methods

We therefore conducted a meta-analysis to compare the pregnancy and perinatal outcomes after day 5 versus day 6 SFBT. Pregnancy and perinatal outcomes of SFBT included HCG positive rate, clinical pregnancy rate (CPR), live birth rate (LBR), miscarriage rate (MR), multiple pregnancy rate (MPR), ongoing pregnancy rate (OPR), ectopic pregnancy rate (EPR), mean bir

SUBMITTER: Hou W 

PROVIDER: S-EPMC12746211 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature