Clinical implication of peri-seminal vesicle soft-tissue invasion in patients with pT3b prostate cancer.

ABSTRACT:

Background

Prognosis of patients with prostate cancer seminal vesicle invasion (SVI) varies considerably, suggesting that SVI may be a heterogeneous pathological entity. This study aimed to perform a detailed histopathological analysis of seminal vesicle (SV) specimens in prostate cancer to better characterize SVI and evaluate its clinical significance.

Materials and methods

We retrospectively reviewed a database of robotic prostatectomies performed between July 2020 and December 2024. Since July 2020, a refined histopathological protocol has been employed in which the prostate and SVs are axially sectioned and separated, and the SVs and vas deferens are sectioned along their natural anatomical axis. This approach allowed a detailed assessment of SV stromal invasion, peri-SV

SUBMITTER: Bang S 

PROVIDER: S-EPMC12746261 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature