Brain Pulsation Imaging Using Non-Balanced Steady-State Free Precession With 3D-EPI Readout.

ABSTRACT:

Purpose

To present a new, fast MR imaging method for visualization and quantification of pulsatile displacement in brain tissue and fluid.

Methods

The natural phase-contrast of non-balanced steady-state free precession combined with careful tuning of the intrinsic spoiler gradients is harnessed to measure displacement along specific physical directions. Efficient segmented 3D-EPI allows for whole brain coverage within TR = 0.15 s. Motion sensitive terms are added to the extended phase graph theory and simulations are used to optimize the sequence parameters and to calibrate the phase sensitivity. Pilot data on 4 healthy volunteers are acquired at 7T and analyzed after cardiac retrogating. A set of three 1-min scans with spoiler gradients along orthogonal axes is required to

SUBMITTER: Goa PE 

PROVIDER: S-EPMC12746386 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature