A Multicenter Observational Study for the Establishment of Novel Severity Criteria Including Endoscopic Evaluation for Intestinal Behcet's Disease.

ABSTRACT:

Objective

This study aimed to establish a novel severity classification for intestinal Behçet's disease (BD) (SCIBD) and validate its criteria across multiple institutions.

Methods

Five parameters, including abdominal pain, tenderness, intestinal bleeding, serum C-reactive protein (CRP) level, and endoscopic findings, were identified to assess the severity of intestinal BD. Disease severity was categorized into remission and mild, moderate, or severe disease based on the criteria of each factor. This study also evaluated the correlation among the SCIBD scale, serum biomarkers, former disease activity for intestinal BD (DAIBD), and treatment decisions.

Results

A total of 146 patients with intestinal BD and simple ulcers were retrospectively enrolled from 14 institution

SUBMITTER: Fukui T 

PROVIDER: S-EPMC12746405 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature