Association of orthostatic hypertension identified according to different definitions with cardiovascular disease. The PARTAGE study.

ABSTRACT:

Objective

Diagnostic criteria for an exaggerated BP increase in response to standing (ERTS) are still debated making it difficult to interpret data regarding the cardiovascular risk associated with ERTS. The aim of the present study was to identify the ERTS definition that was most strongly associated with cardiovascular disease.

Design and methods

The study was conducted within the frame of the PARTAGE study, in 920 individuals aged 80 years or older. BP was measured 1 min and 3 min after standing up. Participants were classified into three groups according to whether they had normal response to standing (reference group), orthostatic hypotension, or ERTS defined using 16 different definitions. The risk of adverse cardiovascular outcomes was explored by means of multivariab

SUBMITTER: Palatini P 

PROVIDER: S-EPMC12746773 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature