Prevalence and risk factors of cognitive frailty in people with HIV.

ABSTRACT:

Background

Cognitive frailty (CF, the simultaneous presence of frailty and cognitive impairment) is recognized as a significant predictor of several adverse health outcomes. The objective of this study was to describe prevalence and risk factors for CF in people with HIV (PWH) >50  years.

Methods

This was a cross-sectional observational study including PWH attending Modena HIV Metabolic Clinic (MHMC). Neurocognitive function was measured with Cogstate battery that comprises six domains. Each individual CogState raw score was transformed into z-score after correction for age and sex. Neurocognitive impairment was defined by total global deficit score >0.5. Frailty was assessed by 37-Item frailty index. Scores <0.25 were considered fit or >0.26 as frail.

Results

A total

SUBMITTER: Milic J 

PROVIDER: S-EPMC12746784 | biostudies-literature | 2026 Feb

REPOSITORIES: biostudies-literature