Novel sperm selection device on the basis of microfluidics improves usable blastocyst rates, embryo morphology, and morphokinetic patterns: sibling cohort prospective study.

ABSTRACT:

Objective

To assess the performance of a novel microfluidic sperm selection device, SwimCount Harvester (SCH), compared with the Swim-up (SU) method, analyzing both sperm quality and the laboratory's key performance indicators.

Design

Prospective, double-blind study using sibling oocytes.

Subjects

This study included 100 patients undergoing intracytoplasmic sperm injection. Both partners had normal karyotypes. Male participants provided only fresh ejaculated semen samples without total asthenozoospermia, globozoospermia, azoospermia, or cryptozoospermia. Female partners had at least 2 mature oocytes retrieved.

Exposure

Semen samples were analyzed to assess concentration, total progressive motile count, vitality, morphology, chromatin structure integrity, and de

SUBMITTER: Meseguer F 

PROVIDER: S-EPMC12746890 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature