A clinical nomogram for predicting major adverse cardiovascular and cerebrovascular events in elderly Chinese patients with acute coronary syndrome undergoing percutaneous coronary intervention: development and validation in a real-world cohort.

ABSTRACT:

Background

As the global population ages, the number of elderly patients with acute coronary syndrome (ACS) rises. However, prognostic assessment tools for elderly patients with ACS remain lacking, particularly in the Chinese population. This study aimed to develop and validate a nomogram to predict 2-year major adverse cardiovascular and cerebrovascular events (MACCE) in elderly Chinese patients with ACS.

Methods

A retrospective analysis was conducted using two independent cohorts of ACS patients aged ≥ 65 years who underwent percutaneous coronary intervention: the derivation cohort (n = 1674) and the validation cohort (n = 2333). Candidate predictors were selected using multivariable Cox proportional hazards regression and the Akaike information criterion. A

SUBMITTER: Xu JJ 

PROVIDER: S-EPMC12747820 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature