Adult-onset Still's disease presenting with aseptic meningitis: a case report.

ABSTRACT: Adult-onset Still's disease (AOSD) is a systemic autoinflammatory disorder characterized by high spiking fever, evanescent rash, arthritis, sore throat, and lymphadenopathy. The pathogenesis of AOSD remains unclear. Neurological involvement in AOSD is uncommon. This case report describes an atypical presentation of AOSD complicated by aseptic meningitis, where the true rarity lies in the unusually severe neurological involvement and associated complications, including empty sella. A 56-year-old female was admitted with a one-year history of recurrent high-grade fever, fatigue, accompanied by seizures and episode of altered consciousness lasting for over 17 hours. During the course of hospitalization, she exhibited polyarticular swelling and pain, seizures and impaired consciousness. Labora

SUBMITTER: Li XF 

PROVIDER: S-EPMC12747900 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature