Efficacy and Safety of Sacral Neuromodulation on Patients With Multiple Sclerosis and Lower Urinary Tract Dysfunction: A Systematic Review and Meta-Analysis.

ABSTRACT:

Aim

Treating multiple sclerosis (MS)-related adult neurogenic lower urinary tract dysfunction (ANLUTD) is challenging because conservative treatments are often ineffective. Sacral neuromodulation (SNM) is a promising minimally invasive treatment of ANLUTD. This review assesses the efficacy and safety of SNM for MS-related ANLUTD.

Methods

Studies were identified through electronic searches of PubMed and Scopus from inception to August 9, 2024, supplemented by backward and forward manual searches. All studies included were original articles investigating the impact of SNM on urinary symptoms in patients with MS and ANLUTD. Three independent reviewers assessed the quality of evidence using the Oxford Centre for Evidence-Based Medicine criteria and the ROBINS-I tool.

Results<

SUBMITTER: Ferreira C 

PROVIDER: S-EPMC12748014 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature