Cognitive Assessments in Randomized Controlled Trials of Acute or Secondary Prevention Stroke Treatments 2011 to 2024: A Scoping Review.

ABSTRACT:

Background

Cognitive impairment after stroke is common and associated with poorer outcomes. However, cognition is rarely assessed in acute or secondary prevention randomized controlled trials (RCTs), and those that do have not been systematically synthesized. This review examines how often cognitive end points are used, specific assessments applied, domains tested, and rates of missing cognitive data.

Methods

We performed a search on EMBASE, PsycINFO, MEDLINE and Cumulative Index to Nursing and Allied Health for RCTs involving adult (≥18 years) participants with stroke, published from 2011 to 2024. Abstracts and full-text publications were screened for stroke RCTs with cognitive end points. These were categorized into acute, secondary prevention, and rehabilitation trials. D

SUBMITTER: Sujanthan S 

PROVIDER: S-EPMC12748075 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature