Bleeding Risk With Combining Antiplatelets and Anticoagulants for Secondary Stroke Prevention: A Propensity Score-Matched Analysis.

ABSTRACT:

Background

Limited data exist on the safety of combining antiplatelets and anticoagulants for secondary stroke prevention in acute ischemic stroke (AIS). We sought to examine the hemorrhage risk with combining single (SAPT) or dual antiplatelet therapy (DAPT) with anticoagulants in patients with AIS with concomitant atrial fibrillation and acute myocardial infarction.

Methods

This retrospective cross-sectional cohort study used TriNetX to collect data from 76 hospitals in the United States. Adult patients with diagnoses of AIS, atrial fibrillation, and acute myocardial infarction were identified using International Classification of Diseases, Tenth Revision (ICD-10) codes. Propensity score-matched analysis, compared the odds for acute spontaneous intrace

SUBMITTER: Farrokh S 

PROVIDER: S-EPMC12748079 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature