A prospective association between dietary phytate intake and risk of fracture in middle-aged and older adults: a 12-Year prospective cohort study.

ABSTRACT:

Aim

This study aimed to investigate the association between dietary phytate intake and the incidence of bone fractures among adults aged over 50 years.

Methods

Particpants of the third (2006-2008) and fourth (2009-2011) phases of the Tehran Lipid and Glucose Study (n = 1917, mean age 59.1 ± 7.1 years, and 50.1% men) who had completed dietary data were included and followed through March 2018 for the incidence of any fracture requiring inpatient care. Cox proportional hazards models were conducted to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) for incident fractures across tertile categories (< 1770, 1770-2598, and > 2598 mg/d) and per each 500 mg/d increase in dietary phytate intake.

Results

During a median follow-up period of 11.5 years (interquar

SUBMITTER: Bahadoran Z 

PROVIDER: S-EPMC12748286 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature