Trends and disparities in mortality associated with peripheral artery disease and hyperlipidemia, 1999-2024.

ABSTRACT: Peripheral artery disease (PAD) with hyperlipidemia adds significantly to the national burden of cardiovascular disease. However, population-level trends in mortality for these conditions are not well understood. We used nationally representative data to investigate long-term temporal patterns and disparities in PAD and hyperlipidemia related mortality in the United States. This descriptive analysis analyzed death records from the CDC WONDER database from 1999 to 2024. The age-adjusted mortality rates (AAMRs) per 100,000 people were calculated for each demographic and geographic strata. AAMRs were standardized to 2000 U.S. standard population. Temporal trends in AAMRs were analyzed using Joinpoint regression to estimate the average annual percent change (AAPC) with 95% confidence intervals

SUBMITTER: Khan S 

PROVIDER: S-EPMC12748544 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature