IgE-mediated sensitizations to Blomia tropicalis allergens in Malaysian allergic population.

ABSTRACT: Allergic sensitizations to Dermatophagoides pteronyssinus and Dermatophagoides farinae house dust mite (HDM) species are continuously on the rise in Asian countries. Whereas the role of Blomia tropicalis, a mite species widely distributed in South/Southeast Asia, in the development of allergic diseases is well evidenced, the association between Blomia sensitizations and allergic symptoms remains poorly investigated in Malaysia. This cross-sectional study characterized the prevalence of sensitization to the clinically relevant Blomia tropicalis mite in cohorts of 329 subjects from the Klang Valley or East Coast Malaysia and developing allergic symptoms. Total specific IgE to Blomia was assayed by ImmunoCAP, IgE reactivities to recombinant Blo t 2, 5, 7, 21 were determined by ELISA IgE assay

SUBMITTER: Olajide AT 

PROVIDER: S-EPMC12748561 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature