Functional outcomes of hypothermic robot assisted radical prostatectomy using BELLOCOOL in a randomized controlled trial.

ABSTRACT: Hypothermia during robot-assisted radical prostatectomy (RARP) has been proposed to enhance functional recovery. This study aimed to assess the efficacy of BELLOCOOL-induced hypothermic RARP for improving urinary continence and erectile function. A total of 200 patients with cT1-T3aN0M0 prostate cancer, eligible for bilateral nerve-sparing surgery, were enrolled across three tertiary centers and randomized 1:1. Stratification was based on International Index of Erectile Function (IIEF-5) scores (≥ 12). The primary endpoint was continence status at 6 months, defined by the use of < 1 pad versus ≥ 1 pads daily. Secondary endpoints included continence and erectile function recovery and safety assessment using the Clavien system. The primary outcome showed no significant difference between gro

SUBMITTER: Han JH 

PROVIDER: S-EPMC12748621 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature