Neural correlates of postoperative pain in patients with rotator cuff tear following arthroscopic surgery: a resting-state fMRI study.

ABSTRACT: This study aims to explore the neural correlates of postoperative pain and its relationship with preoperative psychological issues in patients with rotator cuff tear (RCT). Functional MRI data were collected from 78 RCT patients and 48 healthy controls (HC). Voxel-wise comparisons assessed regional homogeneity (ReHo) differences between groups. Pearson correlation and mediation analyses investigated the links between clinical data and brain changes. Additionally, machine learning using support vector machines (SVM) classified RCT patients based on postoperative pain intensity. RCT patients showed functional alterations in brain areas such as the dorsal anterior cingulate cortex (dACC), primary somatosensory cortex (SI), precuneus, and cerebellum. Increased depression levels correlated posi

SUBMITTER: Chu X 

PROVIDER: S-EPMC12748635 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature