Mpox due to monkeypox virus clade Ia infection detected outside of Africa: a case study.

ABSTRACT:

Background

Monkeypox virus clade Ia has historically been restricted to central Africa and primarily associated with zoonotic transmission. In February 2025, a symptomatic adult with recent travel to the Democratic Republic of the Congo presented to a tertiary care facility in Ireland and was subsequently diagnosed with monkeypox virus clade Ia infection. We describe the clinical, laboratory, phylogenetic and epidemiologic features of this case.

Methods

Diagnostic testing was performed on the 5th of February using real-time polymerase chain reaction. The patient was admitted to the National Isolation Unit, and comprehensive contact tracing with active surveillance was implemented. Whole-genome sequencing was performed to determine the viral lineage and conduct phylogenetic a

SUBMITTER: Dowling-Cullen C 

PROVIDER: S-EPMC12748866 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature