Humoral immunity and clinical characteristics of Chinese college students experiencing a BA.5/BF.7 and XBB.1.5 wave.

ABSTRACT: To investigate the humoral immunity and clinical characteristics of Chinese college students after experiencing a BA.5/BF.7 and/or XBB.1.5 wave. We enrolled 876 college students who received 2-3 vaccination doses of COVID-19 and followed by BA.5/BF.7 and/or XBB.1.5 breakthrough infections between January 2022 and October 2023. IgG and total antibodies against SARS-CoV-2 were measured by chemiluminescent immunoassay. Neutralizing antibodies were detected using a pseudovirus neutralization assay. Meanwhile, we created an Enterprise WeChat link for college students to self-report SARS-CoV-2 infections and clinical symptoms of COVID-19. We observed that among college students, the most common symptoms upon SARS-CoV-2 infection were fever, fatigue, and sore throat. Moreover, reinfected college

SUBMITTER: Xie Y 

PROVIDER: S-EPMC12748907 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature