Peptidomics analysis of serum in patients suffered from generalized anxiety disorder.

ABSTRACT: To identify the differentially expressed peptides that influenced the generalized anxiety disorder (GAD) by adopting peptidomics and to further provide new targets for the diagnosis and treatment of clinical GAD. 20 patients with GAD as the experimental group and 20 healthy volunteers as the control group were included in the experiment. Differentially expressed peptides were compared and analyzed after collecting serum samples from the two groups and performing peptidomics testing. In addition, GO analysis, COG analysis, and enrichment pathway analysis were utilized to explore the biological processes and function distribution of the differentially expressed peptides. A total of 1149 significantly differentially expressed peptides were identified in the sera of patients with GAD compared

SUBMITTER: Zhang J 

PROVIDER: S-EPMC12748909 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature