AI-based prediction of VO₂ max from 24-h Holter ECG recording.

ABSTRACT: Cardiovascular (CV) deconditioning is a consequence of spaceflight, characterized by functional and structural changes in the heart and blood vessels due to prolonged exposure to microgravity. These adaptations lead to a noticeable reduction in exercise capacity, particularly evident in alterations of maximum aerobic power (VO₂ max [mL/kg/min]). This work explored the hypothesis that microgravity-induced CV deconditioning could be anticipated through information derived from a non-exercise longitudinal 24-h Holter ECG recording, thereby offering a means for its regular monitoring in space. Pooled data acquired at baseline and at the last day of six Head-Down Tilt bed rest campaigns of different duration were utilized to test this hypothesis. Machine Learning models were develope

SUBMITTER: Solbiati S 

PROVIDER: S-EPMC12748967 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature