The use of angiotensin-converting enzyme inhibitors in hospitalized patients with COVID-19 is associated with a lower risk of mortality.

ABSTRACT: The relationship between the use of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs), diabetes mellitus (DM), and the risk of death in patients with COVID-19 remains controversial. We hypothesized that DM and certain characteristics of the COVID-19 course during hospital treatment may alter the assessment of the association of ACEIs/ARBs with COVID-19 outcomes. The records of 153 COVID-19 inpatients admitted to a municipal clinic in Kyiv, Ukraine, between October and December 2021 were reviewed. To assess the association of ARBs/ACEIs and other hypotensive drugs with outcomes, a no hypotensives group was used for comparison. A multivariable logistic regression model was employed to assess the odds ratio (OR) of death. If DM was known at the time

SUBMITTER: Khalangot M 

PROVIDER: S-EPMC12749046 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature